منابع مشابه
Genetic analyses of a seasonal interval timer.
Seasonal clocks (e.g., circannual clocks, seasonal interval timers) permit anticipation of regularly occurring environmental events by timing the onset of seasonal transitions in reproduction, metabolism, and behavior. Implicit in the concept that seasonal clocks reflect adaptations to the local environment is the unexamined assumption that heritable genetic variance exists in the critical feat...
متن کاملPERIOD–TIMELESS Interval Timer May Require an Additional Feedback Loop
In this study we present a detailed, mechanism-based mathematical framework of Drosophila circadian rhythms. This framework facilitates a more systematic approach to understanding circadian rhythms using a comprehensive representation of the network underlying this phenomenon. The possible mechanisms underlying the cytoplasmic "interval timer" created by PERIOD-TIMELESS association are investig...
متن کاملA PER/TIM/DBT interval timer for Drosophila's circadian clock.
Circadian rhythms in Drosophila are supported by a negative feedback loop, in which PERIOD (PER) and Timeless (TIM) shut down their own transcription as they translocate once a day from the cytoplasm of clock-containing cells to the nucleus. Period length is partially determined by an interval of cytoplasmic retention of the TIM and PER proteins. To study this process, we examined PER/TIM/Doubl...
متن کاملA plastic interval timer synchronizes pubertal development of summer- and fall-born hamsters.
Summer and fall decreases in day length induce reproductive regression in adult hamsters and delay reproductive maturation of their young. The following year pubertal development is triggered by an interval timer (IT) that renders animals refractory to inhibitory short day lengths after approximately 25 wk. Timing of gonadal and somatic development was examined among offspring born to Siberian ...
متن کاملCell Timer/Cell Clock
Like the biological clock in the body, replication of each cell type (even different cells of the same organism) follows a timing program. Abnormal function of this timer could be an alarm for a disease like cancer. DNA replication starts from a specific point on the chromosome that is called the origin of replication. In contrast to prokaryotes in which DNA replication starts from a single ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: IEEE Transactions on Nuclear Science
سال: 1984
ISSN: 0018-9499,1558-1578
DOI: 10.1109/tns.1984.4333236